Neural Cell Adhesion Molecule N-cam Inhibits Astrocyte Proliferation After Harm To Totally Different Regions Of The Adult Rat Mind Pmc

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When autocomplete outcomes can be found use up and down arrows to review and enter to select. Esportsinsider.com must review the security of your connection before proceeding. Janzer RC, Raff MC. Astrocytes induce blood-brain barrier properties in endothelial cells. Alonso G, Privat A. Reactive astrocytes concerned in the formation of lesional scars differ within the mediobasal hypothalamus and in different forebrain regions. Kitamura T, Tsuchihashi Y, Fujita S. Initial response of silver-impregnated “resting microglia” to stab wounding in rabbit hippocampus.

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  • Rudge JS, Silver J. Inhibition of neurite outgrowth on astroglial scars in vitro.
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  • Janzer RC, Raff MC. Astrocytes induce blood-brain barrier properties in endothelial cells.

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Miyake T, Hattori T, Fukuda M, Kitamura T. Reactions of S-100-positive glia after damage of mouse cerebral cortex. Miyake T, Hattori T, Fukuda M, Kitamura T, Fujita S. Quantitative studies on proliferative modifications of reactive astrocytes in mouse cerebral cortex. Kniss DA, Burry RW. Serum and fibroblast progress factor stimulate quiescent astrocytes to re-enter the cell cycle. Hunter KE, Ssex MB, Davies AM. Transforming progress factor-betas inhibit mitogen-stimulated proliferation of astrocytes. Topp KS, Faddis BT, Vijayan VK. Trauma-induced proliferation of astrocytes within the brains of younger and aged rats.

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After a penetrating lesion in the central nervous system, astrocytes enlarge, divide, and participate in creating an surroundings that adversely impacts neuronal regeneration. We have recently shown that the neural cell adhesion molecule (N-CAM) partially inhibits the division of early postnatal rat astrocytes in vitro. Animals have been lesioned within the cerebral cortex, hippocampus, or striatum with a Hamilton syringe and needle at defined stereotaxic positions. On one facet, the lesions have been concomitantly infused with N-CAM or with one of the N-CAM-related molecules.

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